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Aptensio XR 40 mg

420.00

Quantity

Description

APTENSIO XR is a central nervous system (CNS) stimulant. APTENSIO XR capsules contain multi layered beads, which are composed of an immediate-release layer which contains approximately 40% of the methylphenidate dose, and a controlled release layer which contains approximately 60% of the methylphenidate dose. APTENSIO XR is available in seven capsule strengths. Each extended-release capsule for once-a-day oral administration contains 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, or 60 mg of methylphenidate HCl USP, which is equivalent to 8.6 mg, 13.0 mg, 17.3 mg, 25.9 mg, 34.6 mg, 43.2 mg, or 51.9 mg of methylphenidate free base, respectively. Chemically, methylphenidate HCl is d,l(racemic) methyl α-phenyl-2-piperidineacetate hydrochloride. Its molecular formula is C14H19NO2●HCl. Its structural formula is:

Structure

Methylphenidate hydrochloride USP is a white to off-white, odorless, fine crystalline powder. Its solutions are acid to litmus. It is freely soluble in water and in methanol, soluble in alcohol, and slightly soluble in chloroform and in acetone. Its molecular weight is 269.77.

Inactive Ingredients: sugar spheres, hypromelloses, polyethylene glycol, ammonio methacrylate copolymer, type B; methacrylic acid copolymer, type C; triethyl citrate, talc, colloidal silicon dioxide (added if necessary), titanium oxide, and gelatin.

Each strength capsule also contains colorant ingredients in the capsule shell as follows:

10 mg: FD&C Blue No. 1
15 mg: D&C Red No. 28, D&C Yellow No. 10, FD&C Red No. 40
20 mg: D&C Red No. 33, D&C Yellow No. 10
30 mg: FD&C Blue No. 1, FD&C Red No. 3
40 mg: D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40
50 mg: D&C Yellow No. 10, FD&C Green No. 3
60 mg: Black Iron Oxide

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